HY02455234
BREAKING THE WALL OF PARAPLEGIA: HOW NEUROSCIENCE CAN HELP SPINE- AND BRAIN-INJURED PATIENTS
In the brain and spinal cord, regrowth of injured nerve fibers happens only to a very limited extent. Previously this meant recovery after injury was impossible-but new experimental therapy has allowed regeneration of injured nerve fibers in rats with broken backs, leading to significant recovery of function. In this video from the 2009 Falling Walls Conference, Martin E. Schwab lectures on his discovery that the spinal cord and brain contain the protein Nogo-A, which has a strong inhibitory effect on the growth of nerve fibers. Schwab first purified Nogo-A and then produced function-blocking antibodies which defeat this growth-inhibiting signal. The functions that the rats, mice, and monkeys had lost after spinal cord or brain injuries, such as locomotion, swimming, climbing, and fine hand-reaching movements all returned, indicating that these antibodies could help reduce severe disability in human patients.
DVD
16 minutes
2009
USD 129.95
 
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